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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RUNX1 All Species: 9.09
Human Site: S304 Identified Species: 20
UniProt: Q01196 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01196 NP_001001890.1 453 48737 S304 A P D L T A F S D P R Q F P A
Chimpanzee Pan troglodytes XP_531447 467 50347 S318 A P D L T A F S D P R Q F P A
Rhesus Macaque Macaca mulatta XP_001087338 453 48702 S304 A P D L T A F S D P R Q F P A
Dog Lupus familis XP_858942 453 48730 G304 A P D L T A F G D P R Q F P A
Cat Felis silvestris
Mouse Mus musculus Q03347 451 48591 F303 T A P D L T A F G D P R Q F P
Rat Rattus norvegicus Q63046 450 48538 F302 T A P D L T A F G D P R Q F P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989459 472 51671 D323 S E L G P F S D P R Q F T S I
Frog Xenopus laevis Q6PF39 462 50351 G311 A F S D P R V G I D R Q F S T
Zebra Danio Brachydanio rerio NP_571678 451 48407 L301 L E R S F P S L P S L P D G R
Tiger Blowfish Takifugu rubipres NP_001027815 463 50317 P313 S S D L S P F P G Q F D R Q F
Fruit Fly Dros. melanogaster Q9W349 826 84703 A560 H H P H A H H A H A H L Q H Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 99.7 98.9 N.A. 95.5 95.3 N.A. N.A. 65 87.6 72.8 63.7 24.2 N.A. N.A. N.A.
Protein Similarity: 100 96.7 100 99.5 N.A. 96.4 96.2 N.A. N.A. 75.6 91.3 80.5 77.1 32.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 0 0 N.A. N.A. 0 26.6 0 20 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 6.6 6.6 N.A. N.A. 13.3 26.6 0 33.3 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 19 0 0 10 37 19 10 0 10 0 0 0 0 37 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 46 28 0 0 0 10 37 28 0 10 10 0 0 % D
% Glu: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 10 10 46 19 0 0 10 10 46 19 10 % F
% Gly: 0 0 0 10 0 0 0 19 28 0 0 0 0 10 0 % G
% His: 10 10 0 10 0 10 10 0 10 0 10 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 46 19 0 0 10 0 0 10 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 37 28 0 19 19 0 10 19 37 19 10 0 37 19 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 10 46 28 10 10 % Q
% Arg: 0 0 10 0 0 10 0 0 0 10 46 19 10 0 10 % R
% Ser: 19 10 10 10 10 0 19 28 0 10 0 0 0 19 0 % S
% Thr: 19 0 0 0 37 19 0 0 0 0 0 0 10 0 10 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _